At work, i'm responsible of maintaining something like 60 desktop computers up and running. To keep track of their state, I use Nagios. It's not a bad tool, but its interface is ugly and quite unintuitive, and it lacks some features.
Last month, a new version of Zenoss was released. Zenoss is a full monitoring suite based on SNMP. It is rumored to scale well, track the hosts' states with more accuracy and be visually more appealing. It looked like a nice alternative, so I tried to set it up to replace Nagios.